Background: The prevalence of chronic leg ulcers is increasing at a rapid pace due to lifestyle disorders like diabetes, atherosclerosis. Treatment of chronic leg ulcers is expensive. For a proper treatment of patients with leg ulcers it is important to be aware of the large differential diagnosis of leg ulceration and to effectively manage the conditions Materials and methods: 250 patients with chronic ulcers over leg who presented to the Department of Surgery, Government General Hospital, Guntur, from Sept 2021 to Oct 2023 were included in the study. Results: Males were predominant than females and most of the patients were middle to elderly age group. Diabetic foot ulcers were the majority of ulcers, followed by ulcers due to venous insufficiency and arterial occlusion. Conclusion: A correct diagnosis is neccessary to avoid inappropriate treatment that may cause deterioration of the wound and delay wound healing. With increasing medical technology, newer modalities of treatments for patients with chronic leg ulceration are emerging, so that they can have better quality life.