European Journal of Cardiovascular Medicine

Background: Magnesium has been known to have an influence in the causation of acute myocardial infarction (AMI) and plays a major role in the pathogenesis of other cardiovascular diseases. The present study was undertaken to evaluate the significance of serum magnesium in AMI and compare them with healthy adults and study its correlation with arrhythmias. Method: Total 62 cases and 62 controls were studied in the tertiary care hospital in centralIndiaover a period of around 2 years from December 2020 to December 2022. Results: The mean age of study subjects was 55.74±9.27years with male predominance (75.81%). Systematic hypertension (40.32%) and diabetes mellitus (32.26%)were the most common risk factors. All the patients presented with chest pain on admission. The anterior wall MI predominated in the study followed by inferior wall MI. The mean serum magnesium levels in cases were 1.98±0.33 and 2.26±0.18 in controls, (p<0.05). 14.5% of cases had hypomagnesemia. Serum magnesium in patients with Arrhythmias was 1.57±0.44 and patients without Arrhythmias was 1.99±0.32, (p<0.0049HS). Serum magnesium levels in patients who expired was 1.80±0.42 and in those who survived was 1.96±0.35 (p>0.05). Serum magnesium levels were correlated with development of complications like cardiogenic shock, congestive cardiac failure, complete heart block but it was reported not statistically significant association.Conclusion: Serum magnesium levels were found to be significantly lowin patients with AMIand in patients who develop arrhythmia. Serum magnesium levels were not found to be significantly lower in cases those who expired, therefore it did not have correlation with the mortality.