European Journal of Cardiovascular Medicine

Introduction- Ovarian cancer is one of the ten most commonly diagnosed cancers in women and has the highest mortality rate and the worst prognosis of all gynecological cancers. In 2018, 295,414 cases of Ovarian cancer were detected worldwide, and 184,799 died, with the highest incidence in developed countries. The mortality rate has not changed in the past 30 years, and it is predicted that by 2040, this rate will be significantly increasing. Materials And Methods- Study based on proper clinical examination, radiological investigation, histopathological diagnosis and hematological investigations and Measurement of serum CA-125 and HE4 will be carried out by ELISA method. Results- out of 50 neoplastic lesions 31 cases are benign tumours, 02Borderline and 17 cases are malignant. Conclusion-We concluded High ROMA Index Value shows malignancy. Low value of ROMA index cases are benign so that ROMA Index is helpful to differentiate     in benign and malignant lesion preoperatively