European Journal of Cardiovascular Medicine

Introduction: Malaria continues to be one ofthe biggest health problems inthe Indian subcontinent with 95% of our population is living at risk of infection.Several common complications associated with this disease include anaemia, thrombocytopenia, hepatological changes causing deranged liver and renal function tests. Complication corresponds with the parasitic density determined microscopically. Aim: To study the relationship between parasitic density with haematological parameters, liver function test and kidney function tests. Material & methods: Total 52 malaria falciparum cases studied, diagnosis was by thick and thin smear preparation. Parasitic density was determined according to WHO criteria. Haematological parameters determined by smear microscopy. Liver function and renal function tests were performed by fully automated biochemistry analyser. Results: Out of total 52 cases mean haemoglobin level is 10.10gm%. serum ALT AST level increases with level of parasitemia. Renal involvement seen in later stage and only in moderate and high parasitemia. Conclusion: Malaria complications are directly proportional to the parasitic density and disease spectrum changes with level of parasitemia. Initially cerebral involvement is most common findings in falciparum cases but nowadays liver followed by kidney injury is becoming common presentation.