Contents
Download PDF
pdf Download XML
311 Views
138 Downloads
Share this article
Research Article | Volume 13 Issue:2 (, 2023) | Pages 574 - 579
A prospective observational study regarding pregnancy outcomes between anti TPO antibody positive and negative mothers in sub Himalayan region
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
May 6, 2023
Abstract

Background: Thyroid dysfunction is the second most prevalent medical disorder which has impact on reproductive health and pregnancy outcome. Because of the link of thyroid auto antibodies with various pregnancy related complications and antithyroid peroxidase antibody (TPO Ab) being most common of all of them, can be used as a surrogate marker for thyroid related adverse pregnancy outcomes. Hence, this present study is designed to further elucidate any association of TPO Ab and TSH levesl with adverse pregnancy outcomes. Aims: The present study was undertaken to determine pregnancy outcomes between TPO Ab positive and negative hypothyroid mothers. Methods: This hospital based observational study was conducted in the Department of Gynaecology and Obstetrics, Raiganj Government Medical College, Uttar Dinajpur, West Bengal, India. 305 hypothyroid pregnant women at 1st trimester were chosen randomly between 1st June 2021 to 31st May 2022. The data was tabulated in Microsoft Excel software and analysed with SPSSV.20 software. Results: Maximum participants belonged to age group 15-20 years i.e. 115 (37.7%), followed by 21-25 years’ age group, 92 (30.2%) Mean age of the participants was 23.30 years. Mothers with high TPO were 127 (41.6%). In our study 74 (24.3%) mothers required 25 mcg Levothyroxin followed by 12.5 mcg required for 58 (19%) mothers. GDM (27.78% vs 12.29%, p <0.001), were significantly higher in TPO Ab positive than TPO Ab negative hypothyroid mothers. Conclusions: Pregnant women with hypothyroidism and positive TPO Ab status were more predisposed to GDM than TPO Ab negative women.

Keywords
Recommended Articles
Research Article
Patterns The study of nutrient foramina in human clavicle
Published: 05/02/2025
Download PDF
Research Article
Fixation of pertrochanteric fracture with proximal femoral nail in adults
Published: 20/09/2018
Download PDF
Research Article
Predictive Value of Serum Uric Acid in Patients with Decompensated Chronic Heart Failure at Tertiary Care Teaching Hospital
Published: 28/12/2016
Download PDF
Research Article
Comparative Study of Dexmedetomidine and Propofol for Sedation in Pediatric Patients Undergoing MRI Scans.
Published: 25/04/2017
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.