European Journal of Cardiovascular Medicine

Background: The prevalence of chronic kidney disease (CKD) has increased in the Indian population during the past three decades. Anaemia is a serious problem in chronic kidney disease due to iron deficiency and low erythropoietin levels. Low haemoglobin levels impact patients' quality of life and raise their risk of cardiovascular disease (CVD) and mortality. Much of the mortality and morbidity in patients with renal failure can be related to the secondary effects of chronic anaemia. Objective: to analyse the effects of normalizing haemoglobin levels with exogenous erythropoietin injection supplement on a patient with anaemia secondary to chronic kidney disease. Methods: 60 patients with chronic kidney disease and anaemiawere observed during this study. As per criteria and after approval from ethical committee study was conducted in our institute. Patients were given erythropoietin alfa on a periodic basis and observed with blood parameters on monthly basis to see the effects of normalization of haemoglobin. Results: Normocytic normochromic anaemia was the predominant type; Diabetes nephropathy was the most encountered form of renal disease followed by chronic glomerular disease and chronic interstitial disease. Improved haemoglobin levels did have statistical end result. Conclusions: Renal anaemia can be corrected with erythropoietin in a chronic kidney disease patient. Regular and consistent dose of exogenous erythropoietin does make significant change in patient’s quality of life as well as improved organ vitality. Iron correction is a must along with erythropoietin to reap its entire benefit.