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Research Article | Volume 13 Issue:3 (, 2023) | Pages 1053 - 1061
Single Center Observational Prospective Study to Assess Right Ventricular Function in Congenital Heart Disease with Large Atrial Septal Defect and Eisenmenger Syndrome Initiated on Angiotensin Receptor - Neprilysin Inhibitor
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Aug. 11, 2023
Abstract

Background: Atherosclerosis is diagnosed, treated, and predicted using lipid profile testing. An increase in the fasting serum cholesterol, triglyceride, or both values is referred to as hyperlipidaemia. Diet, exercise, smoking, and some medications can all have an impact on lipid levels. A sedentary lifestyle is one that is prevalent in modern civilisations and is distinguished by spending the most of the day sitting either at work or at home.  It is thought to contribute to obesity and other illnesses. Objectives: To study and compare the TC, TG, LDL-C, VLDL-C and HDL-C in the sedentary adult females and active adult females. Material & Methods:  100 healthy individuals who worked at various banks, schools, colleges, government and non-government organisations, as well as housewives, made up the study's subjects. All of the participants were female and between the ages of 25 and 45. 50 randomly chosen volunteers with sedentary lifestyles and 50 subjects with non-sedentary/active lifestyles. During individual interviews, a validated, structured questionnaire was utilised to gather information on demographic, socioeconomic, lifestyle, and physical activity patterns. Results: In our study when compared to the normal, healthy lipid profile patterns in active adult females, the evaluation of lipid profile patterns in the sedentary subjects revealed hypercholesterolemia, hypertriglyceridemia as well as decreased HDL-C levels in them. Less active adult females had statistically significantly higher lipid profiles (P-value 0.001) than active adult females. Compared to active adult females who have normal, healthy HDL-C levels, sedentary adult females have lower HDL-C levels. Conclusion: As a sedentary lifestyle increases the risk of hyperlipidaemia, regular lengthier training sessions at a greater working intensity and a low-fat diet should be promoted to significantly lower blood lipid levels and other heart disease risk factors including hypertension and obesity.

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