European Journal of Cardiovascular Medicine

Background: Serum uric acid has been linked to the development of hypertension. It has been known that uric acid has a positive association with blood pressure. Objective: The study aimed to assess the relationship between serum uric acid and blood pressure among patients in a specialized center. Method: This cross-sectional study was conducted from January 2020 to June 2021 at the National Center for Control of Rheumatic Fever & Heart Diseases, Dhaka, Bangladesh. A total of 250 patients were enrolled in this study as study subjects. Data were processed, analyzed and disseminated by using MS Office and SPSS version 23.0 programs as per need Results: The mean age was 39.2±13.7 and 38.3±13.5 years in males and females respectively. The mean systolic blood pressure was higher (132.3±15.6 mmHg) in males whereas the mean diastolic blood pressure was higher (129.4±16.5 mmHg) in females. The mean serum uric acid (288.7±74.44 μmol/l) was higher in males and the presence of hyperuricemia was 5.5% in males and 3.1% in female patients. There was a higher proportion of hypertension (32.1%), general obesity (18.2%), and central obesity (76.73%) in females. The mean systolic (137.1±14.6 mmHg), diastolic (82.4±13.9 mmHg) blood pressure and BMI (28.6±5.6) was higher in patients who have serum uric acid level above 357μmol/l. A significant correlation between uric acid and baseline parameters was observed in both male and female patients. Conclusion: In our study sample, serum uric acid level was an independent predictor of hypertension incidence and longitudinal hypertension development. Non-elderly, in contrast to the elderly had a substantial correlation between uric acid and hypertension. Early detection of elevated serum uric acid levels may play a role in the management of hypertension.the intricacies and establish a comprehensive comprehension of their interaction.