European Journal of Cardiovascular Medicine

Early diagnosis followed by prudent dietary supplementation and drug therapy in these high-risk neonates may provide an opportunity for long-range primary amelioration of risk factors that contribute to the development of CVD in adult life. Present study was aimed to evaluate the cord blood lipid profile level in term neonates and late preterm neonates and its correlation with gestational age. Material and Methods: Present study was single-center, cross-sectional study, conducted in neonates (late preterm and term) were born by vaginal delivery/LSCS with one minute Apgar score > 7. Total cholesterol level TC, triglycerides, high-density lipoprotein HDL, low-density lipoprotein LDL, very low-density lipoprotein VLDL were estimated from Cord blood sample. Results: Out of 150 study subjects, 117 (78%) were born at term, while 33 (22%) were late pre-term neonates. 129 (86%) of the newborns under the study were AGA while 21 (14%) were found to be small for gestational age. 78 (52%) were Male and 72 (48%) were Female. There was a statistically significant difference (p<0.05) between the Term newborns & late preterm newborns with respect to the observed values for Total cholesterol (p<0.05), Triglycerides (p=0.17), HDL (p=0.04), LDL (p<0.05) as well as VLDL (p=0.17). Mean values for TC, triglycerides, HDL, LDL, and VLDL were on higher sides in SGA newborns compared to AGA newborns but the difference between mean values for Total Cholesterol. Difference between mean values of Total Cholesterol (p=0.023), Triglycerides (p=0.039), HDL (p=0.002) & VLDL (p=0.039) were found to be statistically significant (p<0.05) between Males & Females. Conclusion: Cord blood lipid profile values for TC, HDL, and LDL significantly higher ( p<0.05) in late preterm neonates compared to term neonates & were on higher sides in female neonates.