Contents
Download PDF
pdf Download XML
178 Views
95 Downloads
Share this article
Research Article | Volume 13 Issue:3 (, 2023) | Pages 1691 - 1695
Correlation between different cardiovascular risk factors with insulin resistance in psoriasis
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Sept. 13, 2023
Abstract

Background: Psoriasis vulgaris (PV) is a chronic recurrent inflammatory skin disease that occurs in genetically predisposed individuals, influenced by various endogenous and exogenous transducing factors. Objectives: The present study was aimed to assess the relationship between cardiovascular risk factors such as, the pattern of dyslipidaemia and body fat deposition with insulin resistance in Psoriatic patients. Methods: Body mass index (BMI) and waist circumference (WC) were measured in 40 psoriaitic patients against matched controls. Fasting Blood Glucose (FBG), Triglyceride (TG), Cholesterol(CHOL), Low density lipoprotein(LDL), Very low density lipoprotein(VLDL), High density lipoprotein(HDL), hsCRP were measured by spectrophotometry. Homocysteine was measured by immune fluroscene technology. Insulin resistance was assessed by measuring the HOMA-IR values. Results: FBG, HDL and WC between this two groups were statistically not significant (p value=0.271, 0.21 and 0.72 respectively). On the other hand, BMI, HOMA-IR, TG, CHOL, LDL, VLDL, hsCRP and Homocysteine levels were significantly higher in the case group (p<0.05). Bivariate correlation analysis showed HOMA-IR to be significantly associated with FBG, BMI, WC, Total CHOL and LDL (but not with VLDL, TG and HDL, hsCRP and Homocysteine values). Conclusions: Mainly an increased insulin resistance that is directly related to significantly elevated levels of abdominal obesity and LDL cholesterol levels reflects metabolic derangements in psoriatic patients in this region. We suggest regular monitoring of psoriatic patients for these parameters to avoid the impending cardiovascular risks in them.

Keywords
Recommended Articles
Research Article
Patterns The study of nutrient foramina in human clavicle
Published: 05/02/2025
Download PDF
Research Article
Fixation of pertrochanteric fracture with proximal femoral nail in adults
Published: 20/09/2018
Download PDF
Research Article
Predictive Value of Serum Uric Acid in Patients with Decompensated Chronic Heart Failure at Tertiary Care Teaching Hospital
Published: 28/12/2016
Download PDF
Research Article
Comparative Study of Dexmedetomidine and Propofol for Sedation in Pediatric Patients Undergoing MRI Scans.
Published: 25/04/2017
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.