European Journal of Cardiovascular Medicine

Background: Hypertension is known to be accompanied by various renal and metabolic anomalies. The exact relationship between serum uric acid (SUA) levels and kidney function, especially in hypertensive patients, requires elucidation.Objective: To understand the correlation between SUA levels and kidney function, gauged by the estimated glomerular filtration rate (eGFR), in a sample size of 342 hypertensive individuals.Methods: Employed a cross-sectional design involving 342 hypertensive participants. SUA was determined using the enzymatic colorimetric technique, while the CKD-EPI equation was utilized to evaluate eGFR. Statistical methodologies were used to identify correlations.Results: A notable inverse correlation between SUA and eGFR was established (r = -0.67, p < 0.001). After accounting for confounding factors, increased SUA was identified as an independent predictor of diminished eGFR.Conclusion: In a sample of 342 hypertensive patients, elevated SUA levels were significantly related to a decline in kidney function. Regular monitoring of SUA may be integral for the management of hypertensive patients, but additional research is required to validate these outcomes and understand potential therapeutic directions.