European Journal of Cardiovascular Medicine

Background: Shivering is a frequent side effect in cesarean section (CS) after spinal anesthesia (SA). Pethidine has been considered as the gold standard for post – SA shivering control, but it is contraindicated in breastfeeding women. Methods: This randomized double-blind study was conducted at SDH Hospital Nowshera Rajouri (J&K), from June 2022 to Dec 2022. A total of 160 eligible term parturient women were enrolled and randomly divided into four groups of low dose ketamine (K) tramadol (T), ondansetron (O) and placebo (P). The incidence and severity of shivering and patients’ complication were recorded and compared among the groups. Results: The demographic data of the patients in all the groups was comparable. Shivering was seen in 21 (52.50%) ,8 (20.0%), 24 (60.0), 26 (65.0) in K, T, O and P groups respectively (P<0.0001) Regarding shivering severity that was significant difference among the four groups (P<0.0001) Conclusion – As there was high incidence of shivering in the placebo group prophylactic intervention is CS under SA seems to be necessary. Among the studied groups tramadol was the most effective one followed by a low dose of ketamine and ondansetron.