European Journal of Cardiovascular Medicine

Background: Cardiovascular disease remains the leading cause of death globally, accounting for a significant burden of mortality and morbidity. It affects people of all ages and socio-economic backgrounds, with a particular impact on low- and middle-income countries. Risk factors such as high blood pressure, tobacco use, unhealthy diets, physical inactivity, and obesity contribute to the global prevalence of cardiovascular disease.  Aims and Objectives: The aim of this research was to study and compare the thyroid profile and serum uric acid levels in diabetic and non-diabetic cardiovascular disease patients. Materials and Methods: The present hospital based observational study was carried out Osmania General Hospital and included 44 cardiovascular disease patients. All the patients underwent detailed history taking, thorough clinical examination and relevant laboratory investigations. Thyroid profile and serum uric acid levels were compared between diabetic and non-diabetic cardiovascular patients. Data was collected in MS Excel and presented as numbers and percentages in the form of tables and figures. Results: More than 60% of the patients considered for the study were male. Majority of the patients, nearly two-third (65.91%), were non-diabetic. Of the 15 patients who were diabetic, almost all the patients (86.67%) fell into the Euthyroid category, while  Hypothyroidism and Hyperthyroidism were found in only one patient (6.67%) each. None of the non-diabetic patients from the study had Hyperthyroid. Majority of the non-diabetic patients (86.21%) exhibited Euthyroid state while only 4 non-diabetic patients (13.79%) had Hypothyroidism. Almost all the diabetic patients (93.33%) from the study had normal uric acid levels, while only one diabetic patient (6.67%) had a raised uric acid level. Among the non-diabetic patients, majority of them (89.66%) had normal uric acid levels. Only 3 of the 29 non-diabetic patients (10.34%) had raised uric acid level. Conclusion: There is a strong association between diabetes and cardiovascular disease. However, further research needs to be carried out to in view of thyroid profile and uric acid levels in diabetic and non-diabetic cardiovascular disease.