Introduction: Stroke is one of the most important non communicable diseases causing death. Stroke or CerebroVascular Accident (CVA) is “abrupt onset of a neurologic deficit that is attributable to a focal vascular cause Therefore, the role of lipid profile at the aspect of stroke status and risk assessment also needs to be further discussed. In order to analyse the above issues, our study investigated the association between stroke patients and their lipid profile. Material and Methods: This study included 100 patient admitted in the ward and fulfilling the inclusion criteria. The study consists of history taking, clinical examination and biochemical assay. Study subjects were selected after obtaining consent. Patient were managed according to standard guidelines. Results: Incidence of stroke was greater in males around 71%. The total serum cholesterol concentration was ≥200mg/dl in 62% of our patients. The HDL-C was <60 mg/dl in 87% of patients in our study and among them 43% had <40mg/dl. The VLDL-C was ≥30 in 46% of stroke patients in our study. Apart from dyslipidemia, hypertension was the most significant risk factor (54%) in our study. Conclusion: Dyslipidemia is a tip of iceberg. Lipid profile screening in patients with risk factors like Hypertension, DM, elder people with family history of atherosclerosis diseases etc., can help to provide primary preventive measures. Dyslipidemia, if properly treated being a modifiable risk factor for ischemic stroke, decreases the incidence of stroke due to dyslipidemia. This leads to decreased morbidity and mortality leading to a healthier society.