European Journal of Cardiovascular Medicine

Introduction: Acute pancreatitis (AP) is an inflammatory disease of the pancreas leading to pancreatic edema, bleeding, and necrosis. Acute pancreatitis is the leading cause of gastrointestinal-related hospitalization in most of the developing countries. A growing number of studies have focused on the association between blood glucose levels and AP outcomes of acute pancreatitis. The main aim of our study is to detect the ranges of blood glucose levels in pancreatitis disease.  Material & Methods: This study was carried out after obtaining approval from the institutional ethics committee. A patient under inclusion criteria was selected for the study they were divided into three groups based on the severity of pancreatitis. In Group A 50 patients with mild pancreatitis, Group B 50 patients with moderate pancreatitis and Group C 50 patients with severe pancreatitis. All the patient's sign and symptoms, fasting blood glucose (FBS), postprandial blood glucose (PPBS), hemoglobin (Hb), neutrophils, and lymphocyte count was done. Then the patients were prescribed selective doses Insulin based on the Glycemic index and after 3 months of treatment, all the biochemical parameter investigation were repeated after 3 months. Results: As per the study majority of the patients were male under the age group 51 – 60 years (58.00%) in group A and in groups B & C majority of the patients were under the age group of 61 – 70 years there were 48.00% & 64.00% showing statistical insignificance (p<0.05) respectively. In this study, majority of the patients had Ascites (fluid buildup in the belly) - 148 (98.66%) followed by severe abdominal pain 146 (97.33%) as major symptoms. In group A patients, significant mean reduction was observed in FBS & PPBS 30.10±1.00 & 25.88 ± 0.30 (p<0.05) respectively and no significant was observed in group B & C of FBS and PPBS (p>0.05 respectively. There is no change in Hb, neutrophils, and leukocyte counts in all three groups.  Conclusion: Patients with mild pancreatitis have shown statistically significant reduction in FBS & PPBS levels, as compared to patients with moderate and severe pancreatitis.