European Journal of Cardiovascular Medicine

Background: Eclampsia is a serious medical condition that affects women during pregnancy. Symptoms of eclampsia appear in pregnancy as a condition known as pre-eclampsia, (condition follows a high blood pressure), the condition can go undetected until it develops into eclampsia. This can create additional complications during pregnancy. Each case of eclampsia is unique, and the pregnant woman may share few or no characteristics with other women who develop the condition. Pregnancy histories, Patient age, Family history, Obesity, High blood pressure are major high risk factors for preeclampsia and eclampsia will vary from patient to patient. Materials and methods:The present study was carried out in the Department of Biochemistry, Rama Medical College and Research centre over a period of 1 year. Total 70 patients of pregnancy were selected out of which 30 patients were of normal pregnancy and 40 patients were of pregnancy induced hypertension. Serum uric acid levels were estimated before delivery and after delivery in cases of pregnancy. Pregnant women with recurrent abortions, bad obstetric history, twins, preexisting medical disorders – such as diabetes mellitus, essential hypertension, renal disorders, cardiovascular, thyroid disorders, and liver disease – were excluded from the study. Result:The result showed significantly high blood pressure (SBP-165.81±20.9 VS 125.69±7.24, DBP 109.74±10.41 VS 80.8±5.15) and Blood urea (31.48±2.33mg/dl VS 6.28+/-1.9mg/dl), serum creatinine (0.67±0.52mg/dl VS 0.67±0.03mg/dl), serum uric acid level (6.28±1.9 mg/dl VS 9.48±2.33mg/dl) in pregnancy induced hypertensive women compares to normal pregnant women. In the present study, in PIH, there is elevation of serum uric acid and serum creatinine elevated values are statistically significant. Conclusion:This study concluded that PIH showed significant elevation in the urea, uric acid, and Creatinine levels compared to normal pregnant women, although all parameters’ values for both groups were in the reference values for non-pregnancy.