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Research Article | Volume 13 Issue:3 (, 2023) | Pages 2071 - 2077
A Clinical Study of Acute Pancreatitis in a Tertiary Care Hospital
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Sept. 25, 2023
Abstract

Background: Acute pancreatitis is an inflammation of the pancreas that can have fatal repercussions and include other organs. 10% of people with serious illnesses die before diagnosis and different degrees of the disease can go undiagnosed [1]. Typically, 70% of instances of acute pancreatitis are caused by gallstones and alcohol consumption. Between 35 and 40 percent of instances of acute pancreatitis are caused by gallstones, including microlithiasis [2].

Objectives:

1. To study the age and sex prevalence of acute pancreatitis.

2. To study the various etiological factors of pancreatitis.

3. To study the clinical presentation and outcome of pancreatitis.

Material & Methods: Study Design:  Hospital based prospective observational study. Study area: Department of Department of Gastroenterology, NRI Academy of medical sciences, China kakani, Guntur, Andhra Pradesh. Study Period:  6 months. Study population:  Patients admitted to the department of Gastroenterology with Acute pancreatitis. Sample size: Study consisted a total of 100 subjects. Sampling Technique:   Simple Random sampling. Routine investigations like Complete hemogram, Blood urea, Serum calcium and Serum amylase were performed. USG Abdomen was done routinely to confirm the diagnosis, for evaluation of the biliary tract and for detecting any complications. Contrast enhanced CT Abdomen was undertaken when the diagnosis was doubtful, when USG was not confirmative and when patient failed to improve beyond 72 hours of presentation. Results: In our present study 24% of patients presented   with   hyperglycemia, 16% had raised blood urea nitrogen (BUN), 27% had hypocalcemia, 14% had a WBC count of more than 15,000cells/mm3, and 11% of the patients had elevated AST levels. 89% of the patients had S.Amylase levels more than three times normal i.e.>240 IU/L. Conclusion: Acute pancreatitis is a frequent cause of an acute abdomen. In India, alcohol is the most frequent factor contributing to acute pancreatitis. Males are more likely to get the condition, and it typically manifests in the third decade of life. Biochemical and radiological results supplement the primary clinical diagnosis.

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