European Journal of Cardiovascular Medicine

Background: Graves’ ophthalmopathy (GO) is the most common extra-thyroidal manifestation of Graves' disease and is characterized by multiple ocular symptoms such as eyelid retraction, lid lag, proptosis, elevated intraocular pressure (IOP) and ultimately loss of vision. We aimed to investigate the prevalence of increased IOP in Graves' patients and association with ophthalmic signs and symptoms in north-west of Iran. Materials and methods: It was a hospital based cross sectional analysis conducted in teaching medical college for a period of 18 months from January 2018 to July 2019 in hyperthyroid patients, Consecutive sampling was done. Participants were divided into age groups. Hyperthyroidism was clinically and laboratory confirmed. Intraocular pressure and Dry eye were diagnosed by single ophthalmologist. SPSS version 22 was used for analysis. Chi square test was used to determine the association. Result: Total 90 established hyperthyroidism patients were studied. The study was female preponderance. Increased Intraocular in hyperthyroid patients was found to be statistically significant. The most common presenting eye sign was found to be diminished vision in almost all patients of Hyperthyroidism which was found to be statistically significant. Age progresses the signs tend to increase in hypothyroidism patients. Diminished vision was found to be the most common eye sign among all age groups which was statistically significant. (p<0.05) followed by Upper lid retraction and ptosis. Conclusion: Female was more commonly affected. The maximum number of patients of both sexes was in the fourth decade of their lives. Hyperthyroidism patient had greater chance of ocular manifestation.