European Journal of Cardiovascular Medicine

Background:  To assess the association between vitamin D deficiency and hypothyroidism in a tertiary care center. Methods: Eighty- four subjects of both genders were divided into 2 groups of 42 each. Group I was healthy subjects (control) and group II was hypothyroid group. All were subjected to measurement of serum T3, T4, TSH, serum calcium and serum 25 (OH) D levels. Results: Group I had 22 males and 20 females and group II had 15 males and 27 females. The mean serum calcium level was 10.4 mg/dl and 7.1 mg/dl in group I and group II respectively. The serum 25(OH) vit D was 45.8 ng/dl and 15.3 ng/dl in group I and group II respectively. The mean serum TSH was 3.4 mU/L in group I and 6.2 mU/L in group II. The mean serum T3 was 2.8 pg/ml in group I and 1.5 pg/ml in group II. The mean serum T4 was 1.9 ng/dl in group I and 0.6 ng/dl in group II. The difference was significant (P< 0.05). Conclusions: Patients with hypothyroidism suffered from hypovitaminosis D with hypocalcaemia. All hypothyroid individuals should undergo tests to check their serum calcium levels and check for vitamin D inadequacy.