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Research Article | Volume 13 Issue:3 (, 2023) | Pages 435 - 438
Diagnostic Utility of Immunohistochemical Markers Ck7, Ck 20 and CEA in Surface epithelial Tumors of Ovary
Under a Creative Commons license
Open Access
Received
July 5, 2023
Revised
July 19, 2023
Accepted
July 28, 2023
Published
Aug. 1, 2023
Abstract

Background: Immunohistochemistry is the definitive diagnosis in cases where a definite diagnosis cannot be made morphologically and histologically. IHC helps classify tumors. It also helps to solve the diagnosis problem of benign and malignant tumors. Material And Methods:  We studied 100 different ovarian epithelial tumors over a 2 year period. Three immune markers were included in the study. Result: Out of 100 case 70% are benign and 30%  aremalignant.Serous cystadenoma was most common benign lesion(60%)& among malignant lesions Serous cystadenocarcinoma was most common(60%).83.33% cases of serous carcinoma showed positivity for CK7 & 100% negativity for CK20 & CEA Conclusion: IHC helps to classify and confirm the histological diagnosis. IHC is particularly useful in solving the diagnostic problem of ovarian cancer and is poorly differentiated.

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