European Journal of Cardiovascular Medicine

INTRODUCTION: Obstructive jaundice is a common surgical problem. Occurs due to both benign and malignant conditions.Evaluation in patients with obstructive jaundice was a challenging problem. Presentation of obstructive jaundice patients is late and mostly present after the disease becomes advanced or uncurable Aims And Objectives: To assess age and sex patterns, clinical presentation, and radiological and biochemical patterns in obstructive jaundice patients. Materials And Method: 100 patients with obstructive jaundice were studied. Proformas form was filled an assessment of demographic and clinical patterns in benign and malignant obstructive were observed and radiological findings in benign and malignant obstructive were carried out to assess the operability. Result: we enrolled 100 patients, 18 were male and 82 were female having mean age was 52.58 yr. All patients have icterus, 60% lumping women, and 31% have pruritus. Gallbladder was palpable in 40% of patients which were due to pancreatic and Periampullary malignancy. Our study reveals the most common overall and benign cause of biliary tract obstruction was CBD stone(33%) and the most common malignant is gall bladder carcinoma(31%) followed by Periampullary carcinoma(17%). CBD stonesare treated by CBD exploration(85%) and palliative treatment by ERCP(15%) and the rest of the benign conditions are completely treatable. Among malignant causes of gallbladder carcinoma treated by radical cholecystectomy (16%), cholangiocarcinoma was mostly inoperable, and Periampullary carcinoma by Whipple's procedure (25%). Conclusion Malignant causes of obstructive jaundice outnumbered benign causes. The most common overall and benign cause was Choledocholithiasis and the malignant was gallbladder carcinoma followed by Periampullary carcinoma. Benign causes were prevalent in younger age groups (31-40 yr) and malignant in older age groups (61-70 yr). A common presentation of obstructive jaundice was icterus and palpable gallbladder was indicative of malignant etiology. Ultrasound followed by MRCP/ERCP and CT scan was the investigation of choice. Benign conditions have better outcomes and cure rates while malignant conditions were inoperable (83%).