European Journal of Cardiovascular Medicine

Background: Renal artery stenosis (RAS) is a vascular condition associated with hypertension and renal impairment, necessitating early and accurate diagnosis for optimal patient management. While Doppler ultrasonography has been the conventional imaging technique for assessing RAS, its limitations have led to the exploration of alternative modalities like Computed Tomography Angiography (CTA). This study aimed to evaluate the role of CTA in diagnosing RAS and its correlation with Doppler ultrasonography findings.

Methods: A prospective observational study was conducted at the Department of Radiology, Rajendra Institute of Medical Sciences(RIMS), Ranchi, Jharkhand, from December 2021 to December 2022. The study included 100 consecutive hypertensive adult patients referred for suspected RAS. CTA and Doppler ultrasonography were performed on all patients, and the results were interpreted. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for both modalities. Correlation between CTA and Doppler findings was analyzed using Pearson correlation coefficient.

Results: The study involved 100 participants (mean age: 58.5 ± 10.2 years, male: 58%, hypertension: 72%, diabetes: 35%). CTA demonstrated higher sensitivity (85.4%) and specificity (91.7%) compared to Doppler ultrasonography (sensitivity: 72.8%, specificity: 81.3%). The correlation coefficient between CTA and Doppler findings was 0.836 (p < 0.001), indicating a strong positive correlation.