European Journal of Cardiovascular Medicine

The management of respiratory distress has advanced significantly in recent years. Various ventilatory therapy modes, including continuous positive airway pressure, conventional mechanical ventilation, ultra high frequency jet ventilation, liquid ventilation, surfactant replacement therapy, sophisticated monitoring, and extracorporeal membrane oxygenation, have all improved the outcomes for babies with respiratory distress. The mortality rate for neonates experiencing respiratory distress is 2-4 times higher than that of those without such distress. Material and Method: The Sardar Vallavbhai Patel Post Graduate Institute of Paediatrics (SVPPGIP) and SCBMCH Cuttack were the study's sites. Neonates that are carried straight to homes or are delivered to smaller hospitals in Orissa and are referred for neonatal care are taken care of by this unit. Study participants were 282 consecutive newborn respiratory distress hospitalisations that met the inclusion criteria. Result: All infants had their progress monitored until their demise or release. Each neonate's fate was documented upon their release from the newborn nursery unit, and those with sepsis were divided into two groups: those who lived and those who did not. For the purpose of estimating haemoglobin, total white blood cell count, absolute neutrophil count, and platelet count, 0.5 millilitres of blood were drawn. Before administering antibiotics, a peripheral vein was used to get a sample of blood, preferably 1 millilitre, which was then cleaned off with 70% alcohol and allowed to dry. The samples were then grown both aerobically and anaerobically. 0.5 ml of blood was drawn into a simple tube without the use of EDTA, and the latex agglutination method was utilised to estimate the CRP. Conclusion: The majority of the neonates in the 282 cases of respiratory distress were male, and the majority were delivered vaginally normally. For their gestational age, the majority of the newborns were healthy. Most newborns had respiratory difficulty within the first 24 hours of life, which is known as the early neonatal phase. The most prevalent diagnosis was pneumonia. A positive blood culture and a positive CRP exhibited a high sensitivity value in the diagnosis of pneumonia, and the study group's total mortality rate was 24.11%.