European Journal of Cardiovascular Medicine

Stroke, a common and significant cause of morbidity and death in hospital admitted patients, had multiple risk factors. The present study was conducted to study the association between carotid artery stenosis and coronary artery disease in persons suffering from ischemic stroke and to study the risk factor profile in carotid artery stenosis with and without coronary artery disease (CAD). Methodology: All consecutive patients admitted to Tertiary care hospital with Cerebrovascular accident of ischemic etiology proved with CT Scan of brain were evaluated for presence of significant carotid artery disease (>70% stenosis) using Carotid artery doppler. Results: A total of 96 patients with CT Brain proven ischemic stroke were included in the study. The mean age was 60.90 ± 11.64 years. Hypertension and diabetes were predominant co-morbidities followed by obesity and CKD. The results showed that there was a 15 times increased risk of CAD in those with ischemic stroke and significant carotid artery stenosis in obese patients when compared to healthy individuals. Upon analysis by binary logistic regression analysis, age (Wald: 18.40) had highest association with CAD, followed by LDL (Wald: 15.58), Smoking (Wald: 14.66), Diabetes (Wald: 12.87), and HDL (Wald: 10.36) in descending order. Conclusion: All patients who had ischemic stroke, must undergo through investigations including carotid artery doppler and coronary angiogram to have the maximum benefit of treatment, lesser morbidity and recurrence of stroke.