European Journal of Cardiovascular Medicine

Background : HIV continues to be a major global public health issue, having claimed 36.3 million [27.2–47.8 million] lives so far. The human immunodeficiency virus (HIV) targets the immune system and weakens people's defense against many infections and some types of cancer that people with healthy immune systems can fight off. Low vitamin D levels have been associated with HIV disease progression and HIV-related complications. Materials and Methods: Cases will be selected from patients presenting to KIMS hospital, IPD section with history Of HIV infection considering the inclusion and exclusion criteria. A total of 110 consecutive patients presenting with HIV positive status, whose inclusion and exclusion criteria are fulfilled are considered for study. It’s a single centered, time- bound prospective study carried out for a period of 2 years. Each patient was evaluated with History, clinical examination, and lab investigations.  Results : In the present study involving 110 HIV patients. The mean CD4+ Count (/cu.mm) was 186.86 ± 104.35 and the mean Viral Load (x103) was 55.20 ± 68.61. vitamin D deficiency was present in 96.4% of population. There was a strong positive correlation between CD4+ Count (/cu.mm) and S. Vitamin D (ng/mL). There was a strong negative correlation between Viral Load (x103) and S. Vitamin D (ng/mL). Conclusion: In this study, with deficiency of Vitamin D level there was positive corelation with CD4 Count causing reduction in CD4 Count and negative correlation with viral load causing increased viral load with reduction in vitamin D levels in HIV affected individuals.