European Journal of Cardiovascular Medicine

Vasculitis is a clinico – pathological entity involving all organs. Despite being reported widely, the triggering etiology for the disease appears to be broadly unknown. Emerging evidence linking immunological, infectious, environmental and genetic causes are being increasingly studied with focus on Infectious agents including viruses, bacteria, fungi and parasites. Case series: Here in we assessed three autopsies demonstrating histopathological evidence of vasculitis seen in various organ systems. Relevant clinicopathological details such as demography, course in hospital, gross and microscopic reports were retrieved from the hospital medical records, reviewed and analysed. In two cases vasculitis was observed against a backdrop of fungal infection with the organs affected being the cerebrum in one and lungs of both cases. The third case demonstrated vasculitis of the coronary arteries in a patient with a known history of tuberculosis. Conclusion: The aim of the cases series was to highlight the importance of infections in causing vasculitis in the demographic set up of India along with the need to consider infection – related vasculitis when faced with diagnostic conundrums. Early stage vasculitis are often clinically silent. Hence, early signs of infections should make one vary of vasculitis as a potential complication, thus direct the investigation panel and therapeutic modalities accordingly to prevent fatal outcomes of the disease.