European Journal of Cardiovascular Medicine

Non-alcoholic fatty liver disease (NAFLD), which affects 15–40% of the general population, is currently thought to be the most prevalent liver condition in the western world.¹ An important contributor to liver-related morbidity and mortality is non-alcoholic fatty liver disease, which is becoming more widely known.^2,3 Interest in this condition is growing among academics and clinicians in the relevant basic and clinical science domains due to its potential to progress to cirrhosis and liver failure. Objectives: To assess the clinical and biochemical profile of NAFLD cases. Material & Methods: Hospital based retrospective observational study was conducted in the Department of General Medicine over a Period 1 year. The cases for the study were selected retrospectively who were diagnosed as fatty liver by ultrasound imaging who attended the Department of General medicine. Study consisted of a total of 50 subjects. BMI was calculated as a measure of obesity. After an over-night fast, serum samples were obtained from all subjects for liver function tests, fasting blood glucose (FBS) serum insulin level. Results: FBG > 126 found in 4 patients (8%). OGTT > 200 found in 6 patients (12%). Impaired FBG was present in 9 patients (18%). Impaired OGTT in 11 patients (22%). Overall, diabetes was present in 8 patients (16%). Mild fatty liver is seen in 39 patients (78%). Moderate fatty liver is seen in10 (20%). Severe fatty liver is seen in 1(2%). Conclusion: Early detection, as well as steps to prevent the condition through lifestyle modification may halt the progression of a benign disease to an advanced illness. It is important for physicians and general practitioners to be aware of the clinical, biochemical, and histological profile of IDNAFLD which is such a common liver disorder.