European Journal of Cardiovascular Medicine

Background: Proximal femur fractures present significant challenges in pain management, prompting the exploration of advanced regional anesthesia techniques. This study evaluates the comparative efficacy of Fascia Iliaca Compartment Block (FICB) using Bupivacaine with Dexmedetomidine versus Bupivacaine alone in patients undergoing proximal femur fracture surgery. Methods: This randomized controlled trial involved patients with proximal femur fractures, randomly assigned to two groups: Group 1 (Bupivacaine with Dexmedetomidine) and Group 2 (Bupivacaine alone). The primary outcome measures included time to first rescue analgesia, total amount of rescue analgesia, adverse effects, and Visual Analog Scale (VAS) scores for pain intensity at various postoperative time intervals. Results: The Bupivacaine with Dexmedetomidine group exhibited a significantly prolonged time to first rescue analgesia, reduced total amount of rescue analgesia, and lower incidence of adverse effects, particularly nausea and vomiting. VAS scores for pain intensity were consistently lower in the Bupivacaine with Dexmedetomidine group across all postoperative time points. Conclusion: Fascia Iliaca Compartment Block with Dexmedetomidine as an adjuvant to Bupivacaine demonstrates superior analgesic efficacy, prolonged duration, and a favorable safety profile compared to Bupivacaine alone in proximal femur fracture surgery. This approach offers a promising avenue for optimizing pain management strategies in this patient population.