European Journal of Cardiovascular Medicine

Cardiovascular diseases (CVD) are major contributors to global burden of chronic diseases with 29.3% of global deaths and 9.9% of total disease burden. The diagnosis of the Myocardial infarction (MI) was based upon the electrocardiogram (ECG) and even if not indicated then different cardiac marker for example Serum Aspartate Transaminase (AST)was done for the confirmation of MI. Therefore, the present study was conducted on 50 normal and 100 patients suffering from myocardial infarction attending /admitted to various wards of Manva kheda, Udaipur. Patients with known cases of Diabetes mellitus and obese person were also included in study. The diagnosis of MI was confirmed by ECG changes and cardiac biomarkers. Controls were 50 normal healthy age and sex matched individuals without any major illness and not on any medications. 5 ml blood sample was obtained from both the groups and was subjected to centrifugation for serum separation and appropriate test analysis was performed. The total mean age of controls and patients is 54.64 ± 7.75 and 57.36 ± 11.96 years respectively. The value of serum AST was 25.76 ± 5.82, in which males had 26.08 ± 5.28 and females had 24.5 ± 7.82 IU/L. With biochemical parameters done on MI Patients, AST was 79.51+23.06. The males had 81.57+23.89 and females had 73.32+19.51 IU/L. The t and p value of patients (male) and control (male) was statistically highly significant with 19.25; P<0.001 and t and p value of patients (female) and control (female) was also statistically highly significant 10.57; P<0.001. Hence, concluded that, ASTin myocardial infarction revealed increased serum levels for all patients with myocardial infarction and remained to be a significant marker in predicting MI.