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Case Report | Volume 13 Issue:4 (, 2023) | Pages 475 - 480
Hyperthyroidism in pregnancy with fetal goitrous hypothyroidism treated with intra amniotic levothyroxine administration– A case report
Under a Creative Commons license
Open Access
Received
Aug. 28, 2023
Revised
Sept. 16, 2023
Accepted
Sept. 30, 2023
Published
Oct. 18, 2023
Abstract

Hyperthyroidism in pregnancy with fetal goitrous hypothyroidism is seen when pregnant mothers are on antithyroid medications. We present a similar case. A 32 years old woman was booked early in pregnancy with a history of Grave’s disease on Propylthiouracil. Anomaly scan showed fetal goitre. Foetal medicine consultant opinion taken. With regular scans, the increasing volume of thyroid was noted. Cordocentesis done which revealed high intra amniotic TSH, diagnosis of fetal goitrous hypothyroidism. She received intra amniotic levothyroxine at 3rd trimester. Gradually the volume of goitre reduced. At 39 weeks, she went into spontaneous labor and had normal vaginal delivery with no neonatal complications.The neonate had a transient hypothyroidism which settled in less than two weeks.

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