Background: The present study evaluates the comparative analysis in patients with diaphyseal fractures of the humerus in the adults operated with dynamic compression plating and intramedullary interlocking nailing with focus on their functional outcome results using DASH score and complications. Materials and methods: The present study was conducted at the Department of Orthopaedics, Government general Hospital, Rangaraya medical college, Kakinada, Andhra Pradesh, India for, a period of two years. The study subjects consisted of n = 38 adult patients of fracture shaft of the humerus with indications for surgical management. Results: Among n = 38 subjects, n = 10 (26.31%) cases showed excellent results, n = 12 (31.57%) good, n = 10 (26.31%) fair and n = 6 (15.78%) poor results. Among n = 10 subjects with excellent results, n = 8 (44.44%) were of plating group and 2 (10%) interlocking nailing. In intramedullary nailing group, 6 (30%) patients showed good results, 8 (40%) fair and 4 (20%) poor results. In patients treated by plate fixation, 6 (33.33%) cases showed good results, 2 (11.11%) fair and, 2 (11.11%) poor results. For all the subjects, DASH scoring was in the range of 21-30 in 50% subjects followed by 10 - 20 in 32.14%, 51 - 60 in 10.72% and 31 - 40 in 7.14% cases. In this series, both the methods of treatment (i.e., dynamic compression plating and interlocking nailing showed good functional outcome results. Conclusion: We prefer dynamic compression plating method as the complications are less compared to the interlocking nailing method and also concerning pain and function of the shoulder joint.
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