European Journal of Cardiovascular Medicine

Background: Clinical scoring systems such as the GRACE , TIMI and HEART score can predict major adverse cardiovascular events, but they cannot be used to demonstrate the degree and severity of coronary artery disease. We investigated the potential of these clinical Score in detecting the existence and severity of coronary artery disease based on SYNTAX score. Methods- cross-sectional study was conducted for a period of 1 years from August 2022 to August 2023.  Association between the scores was established by the Pearson’s linear correlation test while the accuracy of the clinical scores versus SYNTAX score was determined with the ROC curve. Results: A total of 150 patients were enrolled. Median GRACE, TIMI and HEART scores were 95, 4 and 6, respectively, whereas the median SYNTAX was 14. When evaluating the ROC curve, we observed that raised levels of all clinical scores could accurately predict a high SYNTAX score (>32). The association of SYNTAX score with HEART, TIMI, and GRACE scores resulted in an area under the receiver operating characteristic ROC curve (AUC) of 0.811 (95% CI 0.72-0.912, p < 0.01), 0.792 (95% CI 0.641-0.972), and 0.761 (95% CI 0.531 0.791), respectively. Conclusion: The clinical scores presented a positive association with the SYNTAX score. The combined use of HEART and GRACE and TIMI, offers good accuracy for detecting angiographic complexity