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Research Article | Volume 14 Issue:1 (Jan-Feb, 2024) | Pages 508 - 514
Role of IPF as an Indicator of Platelet Recovery in Patients with Dengue and Thrombocytopenia
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1
Assistant Professor, SCB Medical college, Cuttack.
2
Senior resident, PGIMER and CH,
3
Assistant Professor, PGIMER and CH.
4
Assistant professor, SCB Medical College, Cuttack.
5
Senior Resident, PGIMER and CH.
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Received
Dec. 4, 2023
Revised
Jan. 2, 2024
Accepted
Jan. 22, 2024
Published
Feb. 3, 2024
Abstract

:  Introduction: Thrombocytopenia is often a dreaded complication of dengue requiring platelet transfusion. The etiology of thrombocytopenia in dengue is multifactorial IPF, a parameter recorded in newer hematology analyzer measures the immature reticulated platelets and it helps in predicting the rate of thrombopoesis and platelet recovery in dengue patients. Aims and Objectives- The study aimed at evaluating role of IPF in predicting platelet recovery in dengue patients. Material and Methods-The present study was a hospital based cross-sectional study done in Pathology department of PGIMER and Capital Hospital Bhubaneswar in the month of October 2023. Platelet count, IPF and platelet parameters were noted for patients of dengue (NS-1 positive) on day 1, 3, 5 and 7. RESULTS- 60% of patients with thrombocytopenia lacked platelet parameters MPV, PDW, PLCR in CBC while all the patients expressed IPF. Patients with high IPF (>10%) demonstrated a faster recovery compared to those with low IPF (<10%). Those with IPF greater than 10% had a gradual decline in IPF with improvement of platelet count. Conclusion: IPF is a consistent and reliable parameter to predict platelet recovery in patients of dengue with thrombocytopenia. It can help in guiding decision making regarding platelet transfusion.

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