European Journal of Cardiovascular Medicine

Background:  Chronic suppurative otitis media (CSOM) is one of the commonest illnesses which require urgent medical treatment especially in children’s of poor socio-economic status. The aim of present study was conducted to evaluate the different aerobic and anaerobic microorganisms causing csom in paediatric and adult patients and their antimicrobial sensitivity pattern as a guide to therapy. Materials and methods: A total of 106 clinically diagnosed cases of csom patients were included in the study, out of which 74 patients belong to paediatric csom and 32 cases were adult csom. From all the patients 106 samples were collected aseptically and processed according to standard CLSI Guidelines. Results: Out of 74 paediatric csom patients,68 patients (91.89%) were bacterial culture positive while out of 32 adult’s csom patients, 26 patients (81.25%) were culture positive. Bilateral csom was slightly more common in adults than paediatric age group. Polymicrobial nature of csom was noted in both paediatric and adult cases while number of organisms isolated per lesion was slightly higher in adults as compared to paediatrics cases. Staphyloccocus aureus was the commonest aerobic isolate in paediatric age groups csom, while in adult Pseudomonas aeruginosa was the commonest one. Among anaerobic culture Peptostreptococcus spp was commonest in paediatrics csom whereas Prevotella melaninogenica in adult csom. Sensitivity of S. aureus to Doxycycline, Clindamycin, Linezolid were 100%, piperacillin + Tazobacatum 94.59%, cefuroxime was 86.48% while that of gram negative bacilli was higher to cefuroxime, ceftriaxone, Azithromycin, Clindamycin, Doxycycline 90 to 100%. Among anaerobes higher sensitivity was seen to metronidazole (100%), clindamycin (100%) and ceftriaxone (100%). Conclusion: In view of the polymicrobial etiology of csom, prompt appropriate antimicrobial therapy can effectively reverse the disease process thereby preventing longterm sequelae.