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Research Article | Volume 14 Issue:1 (Jan-Feb, 2024) | Pages 662 - 671
A Prospective study to Assess the Change in ER/PR/HER-Status Before and After Neoadjuvant Chemotherapy in Carcinoma of Breast
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1
Senior Resident, Department of Radiotherapy : MNJ Institute of Oncology & Regional Cancer Centre,. Red Hills, Lakadikapul,. Hyderabad, Telangana, 500004.
2
Associate Professor, Department of Radiotherapy : MNJ Institute of Oncology & Regional Cancer Centre,. Red Hills, Lakadikapul,. Hyderabad, Telangana, 500004.
3
Assistant Professor, Department of Radiotherapy : MNJ Institute of Oncology & Regional Cancer Centre,. Red Hills, Lakadikapul,. Hyderabad, Telangana, 500004.
4
Professor, Department of Radiotherapy : MNJ Institute of Oncology & Regional Cancer Centre,. Red Hills, Lakadikapul,. Hyderabad, Telangana, 500004.
5
Medical student: Mamata academy of medical sciences : Bachupally, Hyderabad, Telangana 500090
6
Medical student: All American Institute of Medical Sciences, Black river, Jamaica
Under a Creative Commons license
Open Access
Received
Dec. 12, 2023
Revised
Dec. 29, 2023
Accepted
Jan. 17, 2024
Published
Jan. 30, 2024
Abstract

Aims: to compare the effectiveness of epidural Ropivacaine with epidural Levobupivacaine for anaesthesia in lower abdominal and lower limb surgeries. Materials and methods: It is a Hospital based prospective study in 100 patients admitted between age 18-60 years, ASA grade 1 and 2 in Patients undergoing Lower abdominal and Lower limb surgeries  Results: In  the  present  study,  the  mean  age, gender, weight, height, ASA-1 and 2, onset of sensory block, onset of motor block of  the  Levobupivacaine  group  and ropivacaine group was not statistically significant. No  significant  difference observed between the two groups with relation to Highest level of sensory block  achieved. There is significant difference between the two groups, with group L producing a deeper motor blockade (0.02). Mean Duration of Motor block in Group R was 282.98 ± 11.23 and in Group L was 280.54 ± 4.61. This observation was not statistically significant (p=0.64). Mean duration of sensory  analgesia in Group R was significantly prolonged than Group L. This observation was statistically significant (p=0.02).  Both the study groups were hemodynamically stable with relation to pulse rate at 0, 5, 15, 30,  60mins,  2, 6, 12 hours. Higher sedation score was observed in Ropivacaine group compared to Levobupivacaine group. Conclusion: Levobupivacaine can be used as a better alternative to Ropivacaine for epidural anaesthesia in lower abdominal and lower limb surgeries

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