European Journal of Cardiovascular Medicine

Aim of the study: determine the pattern of prescription of Anti Diabetic Drugs in a cohort of patients at a tertiary care centre of East Nimar region of Central India. Methods: The study was a Prospective observational study and was conducted in the Outpatient department of Medicine conducted for a period of 6 Months. Demographic and clinical data of total 82 patients were collected and Prescription of these Diabetic patients were analysed. Result: Out of Total 82 Patients, the maximum percentage of Diabetic patients, including both males and females belonged to the age group of 51 to 60 years (36.58%). Majority of Patients received Two Drug Anti-diabetic Drug combination (i.e. Metformin and Glimepiride combination) which were the most prescribed drugs (65.85%, 54 Patients out of total 82 Patients) followed by Mono-therapy with Metformin (13.41%, 11 Patients out of total 82 Patients). Among the three drugs combination therapy prescribed in 15 patients (18.29%), often Metformin + Glimepiride + Pioglitazone combination were prescribed (6 patients, 7.31%),  followed by Metformin + Glimepiride+ Vildagliptin /Tenegliptin/ Sitagliptin (DPPIV Inhibitors) (5 patients, 6.09 %). As far as comorbid conditions are concerned 62 Patients (75.60 %) had no comorbid disease along with Diabetes, 20 patients (24.39 %) had Hypertension and 3 patients (3.65 %) had Hyperlipidaemia along with Hypertension and Diabetes and received concomitant medications for the same. Conclusions: The present study represents the current prescribing pattern of Anti-Diabetic Drugs in our Hospital. Our findings showed that Metformin and Glimepiride combination dominated thescenario followed by Monotherapy with Metformin among the elderly populations of Diabetes. The use of Anti-Diabetic drugs largely confirms the guidelines as most of the patients belonged to the category of elderly populations, but still there is a significant room of improvement in terms of rational prescribing.