Contents
Download PDF
pdf Download XML
369 Views
175 Downloads
Share this article
Research Article | Volume 14 Issue:1 (Jan-Feb, 2024) | Pages 706 - 717
Correlation of Hypertensive Retinopathy to Serum Lipid Profile in Hypertensive Subjects
 ,
 ,
 ,
 ,
1
Professor and Medical Superintendent, Department of Ophthalmology, Regional Eye Hospital, Kurnool Medical College, Kurnool, Andhra Pradesh
2
Associate Professor, Department of Ophthalmology, Regional Eye Hospital, Kurnool Medical College, Kurnool, Andhra Pradesh
3
Assistant Professor, Department of Ophthalmology, Regional Eye Hospital, Kurnool Medical College, Kurnool, Andhra Pradesh
4
Consultant, Department of Ophthalmology, Hyderabad, Telangana, India.
Under a Creative Commons license
Open Access
Received
Dec. 11, 2023
Revised
Dec. 27, 2023
Accepted
Jan. 17, 2024
Published
Jan. 31, 2024
Abstract

Background This study was conducted to assess the correlation between various serum lipid profile components (total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, VLDL cholesterol, and LDL:HDL cholesterol) and hypertensive retinopathy and its severity. Methods This was a hospital-based cross-sectional clinical study conducted among 100 hypertensive patients attending ophthalmic OPD. The study was undertaken at the Regional Eye Hospital, Kurnool, from November 2017 to October 2019 after obtaining clearance from the institutional ethics committee and written informed consent from the study participants. Results The prevalence of retinopathy increased with the duration of hypertension and showed a significant difference (p<0.0001). Hypertensive retinopathy showed a significant difference (p<0.001) between stages of hypertension. There was a significant difference between the retinopathy group and the non-retinopathy group in various lipid parameters like serum total cholesterol (p < 0.0001), LDL cholesterol (p < 0.0001), serum triglycerides (p = 0.0218) and LDL:HDL ratio (p = 0.0029). The various grades of retinopathy also showed statistically significant differences in various lipid parameters. Higher grades of retinopathy were associated with higher levels of serum total cholesterol (p = 0.035), LDL cholesterol (p = 0.028), serum triglycerides (p = 0.038), and LDL:HDL ratio (p = 0.021). Arcus senilis was higher in the retinopathy group than the non-retinopathy group. There was a significant difference between serum lipid parameters and hypertensive retinopathy (p = 0.045). This shows an association between serum lipid parameters and the prevalence of hypertensive retinopathy. Conclusion Lowering increased serum lipid parameters in hypertensive patients is advisable to preserve sight as well as prevent other end-organ damage. 

Keywords
Recommended Articles
Research Article
A Study on Efficacy of Intralesional Vitamin D3 In Treatment of Cutaneous Warts
...
Published: 07/07/2025
Download PDF
Research Article
Comparative Analysis of VEXUS Score in Traditional Risk Assessment Tools in Emergency Medicine Department
...
Published: 30/10/2024
Download PDF
Research Article
Etiological Profile of Myeloneuropathy in a Tertiary Care Hospital of Northeast India
...
Published: 07/07/2025
Download PDF
Research Article
An Observational Descriptive Study on the Correlation of Renal Cortical Thickness, Renal Echogenicity and Renal Size with Estimated Glomerular Filtration Rate in Chronic Kidney Disease Patients in A Tertiary Care Hospital
...
Published: 05/07/2025
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.