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Research Article | Volume 14 Issue:1 (Jan-Feb, 2024) | Pages 858 - 867
A Study Comparing Dexmedetomidine as an adjuvant to Local Anaesthetic Versus Combination Of Intravenous Midazolam And Pentazocine In Tympanoplasty Surgeries Under Monitored Anaesthesia Care – A Randomized Controlled Study
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1
Assistant professor, Department of Anaesthesia, SVNGMC, Yavatmal
2
Associate Professor, Department of Anaesthesia, SVNGMC, Yavatmal
3
Senior Resident, Department of Anaesthesia, SVNGMC, Yavatmal
4
Jr2, Department of Anaesthesia, SVNGMC, Yavatmal
Under a Creative Commons license
Open Access
Received
Dec. 6, 2023
Revised
Dec. 20, 2023
Accepted
Jan. 2, 2024
Published
Jan. 17, 2024
Abstract

BACKGROUND Tympanoplasty is usually done under local anesthesia with sedation under monitored anesthesia care (MAC) or general anesthesia. This randomized, double-blind study compares dexmedetomidine as an adjuvant to local anaesthetic vs a combination of intravenous midazolam-pentazocine in patients undergoing tympanoplasty Under Monitored Anesthesia Care with respect to-VAS (Visual Assessment Score) and Time required for rescue analgesia in a tertiary hospital in India. MATERIALS AND METHODS This was a prospective, randomized, double blinded, comparative study. All the patients were well informed about study & each one of them gave written informed & valid consent to participate in the study. Total number of patients in the study was 82, with 41 patients in each of the two groups. Grouping done as follows Group Dexmed 10 ml of Bupivacaine + 10 ml of Lignocaine-adrenaline+ Dexmedetomidine 50mcg Group MPInj Midazolam 1.5 mg+ Inj Pentazocine 30mg IV RESULTS The demographic data were comparable in both the groups. Of 41 cases in Group Dexmed, 25 cases (61.0%) had Right CSOM and 16 cases (39.0%) had Left CSOM. Of 28 cases in Group MP, 25 cases (61.0%) had Right CSOM and 16 cases (39.0%) had Left CSOM. Distribution of mean pain score (VAS) at 30 min, 40 min, 50 min, 60 min and 80 min among the cases studied is significantly lower in Group Dexmed compared to Group MP (P-value<0.05 for all). Distribution of no. of rescue sedation injections required among the cases studied is significantly higher in Group Dexmed compared to Group MP (P-value<0.05). Distribution of mean time until the need for rescue analgesia is significantly higher in Group Dexmed compared to Group MP (P-value<0.05 CONCLUSION We found that Dexmedetomidine is more effective as an adjuvant to Local Anaesthetic Versus Combination of Intravenous Midazolam And Pentazocine In Tympanoplasty Surgeries.

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