Transplantation is a surgical procedure in which the organs or the tissues or the cells are removed from one person who is called as the donor, are surgically transplanted in the other person who is called as the recipient. When an organ gets transplanted, it is called organ transplantation. It is the procedure which also impacts the recipients with oral and dental manifestations. Material and Methods: Major databases such as Medline were explored detailed literature search in resulting in a systematic review pertaining to link between oral and maxillofacial pathology and organ transplantation. Results: Five original research scientific articles dated between 2020 – 2024 pertaining to mentioned topic were highlighted. Conclusions: Many recipients may complain that there may be any mucosal infections or lesions. So, the dentists along with transplantation professionals should identify, diagnose and treat the oral and maxillofacial manifestations as early as possible. Detailed information regarding the manifesations of oral and maxillofacial pathology and organ transplantation is discussed in this systematic review.