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Research Article | Volume 14 Issue:1 (Jan-Feb, 2024) | Pages 962 - 966
Endocrine Shock- In COVID 19 -A Review Article
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 ,
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1
Professor, Department of General Medicine, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
2
Associate Professor, Department of General Medicine, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
3
Associate Professor, Department of Paediatrics, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
4
B. Tech, MS (USA)
Under a Creative Commons license
Open Access
Received
Dec. 14, 2023
Revised
Dec. 26, 2023
Accepted
Jan. 10, 2024
Published
Jan. 31, 2024
Abstract

Background:  Human coronaviruses can be divided based on their pathogenicity. The types with high pathogenicity including SARS-CoV, MERS-CoV, and the current novel SARS-CoV2. SARS COV2 has led to possibly the worst pandemic of this century in the form of Coronavirus disease 2019 (COVID-19). Initially recognized as a respiratory system disease, COVID-19 has been found to interact with functions of other organ systems like cardiovascular, GIT, CNS  Peripheral nervous system, during the course of the disease and postcovid syndromic manifestations including Endocrinal and psychological. The acute manifestations primarily lung will be involved that leads to ARDS, in severe disease all the organs will be effected that may lead to multiorgan dysfunction (MODS), and death. AIM: Evaluation of various endocrinal manifestations secondary to endocrinal gland dysfunction, in COVID 19 peak of the pandemic causing morbidity and mortality. In this COVID 19 pandemic everywhere the mortality was very high, the researchers and all over the globe thought that this is not only viral invasion or host’s immune mediated of it’s not due to viral virulence and postulated the actual pathogenesis of the disease and its manifestations causing morbidity and mortality. Some patients with coronavirus disease 2019 (COVID-19) develop a life-threatening hyper-inflammatory state that is commonly referred to as cytokine storm. This is the prime cause of all the syndromes presenting in this SARS COV2. The mortality has been increasing and new biochemical parameters are increasing in moderate to severe disease.

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