European Journal of Cardiovascular Medicine

Aim: The aim of this study was to evaluate the prevalence of maternal and neonatal outcomes with respect to cervical length (CL), amniotic fluid volume, and latency in women with preterm premature rupture of membranes (PPROM). Methodology: The present study was conducted as a prospective observational investigation. All female admitted to the hospital got transabdominal ultrasonography to assess their amniotic fluid index. A minimum of three measurements were obtained, and the measurement with the shortest length was documented. The procedure of cervical measurement entails the insertion of callipers into the space between the external and internal cervical Os. Female admitted patients were given expectant management, which involves the provision of antibiotics and steroids. Resuls: The study population consisted of 90 women with singleton pregnancies at gestational ages ranging from 28 to 36 weeks. Patients in gestational duration of 24 to 28 weeks having cervical index of ≤ 2.5 cm reported the low mean latency duration of 8.95 ± 1.86 days as compared to the cases having >2.5 cm index among the same group. This low gestational group reported high incidence of Chorioamniionitis (10% and 63.3% in cervical index of  ≤ 2.5 cm and >2 cm respectively), 1 min APGAR <7 (26.6% and 73.3%), high incidence of NICU admission (23.3% and 63.3%) and early neonatal death (13.3% and 60%) than the other gestational age groups. Significant differences of <0.0001 was reported between groups (Table 1). Meanwhile, regarding amniotic fluid index the average latency rate in ≤5 cm was reported as 7.43 ± 1.83, 5.12 ± 1.06 and 1.33 ± 0.23 in gestational duration of 24 to 28, 28 to 32 and 32 to 36 weeks. Meanwhile the the high latency rate was observed in all three groups when comparing the amniotic fluid index of >5cm.  Conclusion: The latency period is negatively correlated with gestational duration, meaning that a shorter gestational duration is followed by a longer latency period. An raised amniotic fluid index, which is linked to a higher incidence of chorioamnionitis and neonatal difficulties and is probably caused by a prolonged period of latency, is positively correlated with an extended cervical length.