European Journal of Cardiovascular Medicine

Myocardial dysfunction is one of the most important features of sepsis. The presence of cardiac dysfunc- tion in sepsis has been associated with high mortality rate in septic patients. Material & Methods: This was prospective, observational cohort (patient with severe sepsis and septic shock) study conducted over period of one year in medical intensive care unit. Patients with an initial diagnosis of severe sepsis or septic shock were enrolled. Aims & Objectives: To study demographic pro le, APACHE-II score and echocardiographic parameters in patients with severe sepsis and septic shock and to nd out relation of echocardiographic parameters to variables of sepsis and outcome. Study Popu- lation: All patients underwent laboratory investigations, APACHE-II score and Transthoracic 2- Dimensional echocardio- gram. Statistical analysis: Data was analysed by trial version SPSS-16 for mean, SD, chi-square test with‘p’ <0.05 was considered as statistically signi cant.