Contents
Download PDF
pdf Download XML
582 Views
107 Downloads
Share this article
Research Article | Volume 7 Issue :3 (, 2017) | Pages 17 - 21
Comparison of Urinary calcium levels in adult patients with fracture and surgical intervention and without fracture
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Sept. 15, 2017
Abstract

Background: Fractures, stemming from trauma or medical conditions, pose significant challenges to global healthcare. Despite extensive research on biomechanical aspects, the systemic impact on mineral homeostasis, particularly urinary calcium dynamics, remains understudied in adults undergoing fractures and surgical interventions. Materials and Methods: A prospective observational study conducted at a tertiary medical college in Uttar Pradesh, India, aimed to scrutinize urinary calcium levels in adults with fractures and surgical intervention compared to a fracture-free control group. Participants included adult patients (n=150/group) with fractures requiring surgical intervention and age-matched controls. Serum and urinary calcium levels were assessed, and statistical analyses were performed using appropriate tests. Results: The "Fracture + Surgery" group exhibited lower mean serum calcium levels (9.3 mg/dL) compared to controls (9.7 mg/dL, p<0.001). Urinary calcium levels were significantly elevated in the "Fracture + Surgery" group (175 mg/24h) compared to controls (120 mg/24h, p<0.001). Subgroup analysis based on fracture types revealed nuanced variations in urinary calcium dynamics. Type 2 fractures exhibited the highest mean urinary calcium levels (180 mg/24h, p<0.001). Conclusion: Our study highlights disruptions in calcium metabolism following fractures and surgical interventions, emphasizing the need for comprehensive clinical management. The setting in Uttar Pradesh provides unique insights into diverse patient populations. Future research should explore molecular mechanisms underlying these changes and targeted interventions.

 

Keywords
Recommended Articles
Research Article
Study Of Hematological Abnormalities in Decompensated Chronic Liver Disease
...
Published: 30/06/2025
Download PDF
Research Article
Role of Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria in prediction of clinical outcomes in patients with acute coronary syndrome
...
Published: 30/09/2025
Download PDF
Research Article
Comparison of Intravenous Magnesium Sulphate and Clonidine in Attenuating Hemodynamic Responses during Laryngoscopy and Tracheal Intubation: A Prospective Randomized Double-Blind Study
Published: 30/09/2020
Download PDF
Research Article
A Study Comparing Pre- Operative Prophylactic Iv Antibiotics with Combined IV and Intraincisional Antibiotics Administration for Reducing Surgical Site Infections
...
Published: 27/09/2025
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.