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Research Article | Volume 7 Issue :4 (, 2017) | Pages 1 - 7
Association of HbA 1 C levels and severity of diabetic retinopathy in diabetes mellitus population
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Dec. 5, 2017
Abstract

Objective: This study aimed to investigate the correlation between HbA1C levels and the occurrence and severity of diabetic retinopathy in individuals with type II diabetes mellitus. Methodology: The current study was conducted as a cross-sectional examination. The research encompassed a cohort of 130 persons who were definitively diagnosed with diabetes and sought medical treatment. The data was acquired by conducting face-to-face interviews with the participants. The interviews were conducted by researchers who administered questionnaires that solicited information on demographic and clinical factors. Informed permission was obtained from all participants in the study. The latest recorded values of HbA1c, body mass index (BMI), triglycerides, total cholesterol, and serum creatinine were obtained from the records of each participant.  Results: Our study included a cohort of 130 individuals diagnosed with diabetes who sought medical care at ophthalmology clinics. Among the sample, 111 individuals were identified as having been diagnosed with type 2 diabetes mellitus (DM). The logistic regression analysis has demonstrated a statistically significant association with the risk of DR, as evidenced by a p-value of 0.001. The statistical analysis demonstrated that the significance of HbA1c was consistent, as evidenced by a p-value of 0.040. In contrast, our analysis did not identify any significant association between diabetic retinopathy (DR) and the diverse characteristics investigated, such as gender, family history of diabetes mellitus (DM), smoking habits, hypertension, coronary artery disease (CAD), renal dysfunction, cholesterol levels, triglyceride levels, and serum creatinine levels. Conclusion: In conclusion, our study found that around 26.9% of the patients exhibited manifestations of diabetic retinopathy (DR). A noteworthy correlation was observed between the levels of HbA1c and the length of diabetes mellitus (DM) in the occurrence of diabetic retinopathy (DR) among individuals diagnosed with diabetes.

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