European Journal of Cardiovascular Medicine

One significant member of the Rubiaceae family and a frequently used herb in siddha treatment is Spermacoce hispida Linn. Phytochemical components found in plant extracts include saponins, tannins, phenolics, steroids, essential oils, flavonoids, and terpenoids. This plant's chemical components have been employed for its antidiabetic, antihypertensive, hepatoprotective, anti-inflammatory, antihyperlipidemic, analgesic, antifungal, anticancer, and antioxidant activities. In the current investigation pharmacognostic evaluation and antioxidant potential of Spermacoce hispida was carried out. The outcome of study showed that the methanolic extract of S.hispida had strong hydrogen donating ability with an IC50 value of 60.91 µg/ml, respectively and the value was found to be less than the standard vitamin C (IC50 value of 19.77 µg/ml).