European Journal of Cardiovascular Medicine

Chronic venous ulcer (CVU) is an ulcer on gaiter area persisting for more than six weeks and difficult to heal even after three months of treatment. The prevalence of CVU ranges from 0.18% and 1% and Standard therapy for CVU is multilayered bandages and treatment of incompetent veins to prevent recurrence. All adult patients having CVU, due to primary varicose veins were randomly allocated to two intervention groups (Group A- comprising of use of compression bandages along with treatment of varicose veins by Endovenous Laser ablation and Group B- Non usage of compression bandages after the aforesaid surgical intervention).Out of 60, total 30 (50%) cases were in each group. Quality of life and therapeutic outcomes were noted, and patients were followed for 6 months. Quality of life outcomes compared based on SF-36 questionnaire showed more improvement in group A in all 8 domains. Other parameters like use of analgesics, itching, eczema, and increased leisure activities were better with use of compression bandages. Healing of ulcer was faster in Group A. Charing Cross varicose vein questionnaire also showed more improvement in group A (p value<0.001, <0.001, 0.003   at 1 month, 3 month and 6 month, respectively).In chronic venous ulcer, four-layer compressive bandaging after surgery enhances the healing rate of venous ulcer with better quality of life outcomes.

Background: Varicose veins could be a complicated condition, which may lead to limb swelling, pain, and venous ulcer. Conservative hemodynamic correction of venous insufficiency (CHIVA) has been developed over the past two decades and is currently the second most common surgical procedure for the operative treatment of varicose veins. Endovenous laser treatment of great saphenous vein was approved by FDA in 2002 and short saphenous vein (SSV) was approved in 2003. Endovenous laser ablation (EVLA) is a clinically safe, feasible, and well-tolerated technique without scar and allows people to return to their normal daily activities rapidly. Aims And Objectives:  To study the surgical management (great saphenous vein [GSV] stripping and perforator ligation) and its outcome and compare the outcome of GSV stripping in case of saphenofemoral junction incompetence and perforator ligation in case of perforator incompetence with the results of endoscopic and endovenous procedurespublished in the literature. Results: The patients with varicose veins were treated with high ligation with stripping followed by foam sclerotherapy and RFA. None of the patients undergoing high ligation with stripping had DVT and recurrence which favors the procedure selection for management. However, high ligation with stripping was associated with tenderness followed by infection. complications were less prevalent and only two patients had tenderness. Similarly, in radiofrequency ablation (RFA), one patient each had recurrences, skin color changes, and tenderness. None of the patients undergoing HL/S and foam sclerotherapy had recurrences. It was found that the duration of hospital days was more with HL/S; the majority had 6 to 8 days duration of hospital days whereas 13 patients had it for 4 days. In RFA, the majority had a duration of hospital days of 2 to 3 days only. Conclusion: open surgical management remains important in the treatment of varicose veins and is usually preferable to endovenous procedures and associated with less morbidity if carried out correctly.

Background: Chronic Venous ulcer (CVU) is an ulcer on gaiter area persisting for more than six weeks and difficult to heal even after three months of treatment. The prevalence of CVU ranges from 0.18% and 1% and Standard therapy for CVU is multilayered bandages and treatment of incompetent veins to prevent recurrence. All adult patients having CVU, due to primary varicose veins were randomly allocated to two intervention groups (Group A- comprising of use of compression bandages along with treatment of varicose veins by Endovenous Laser ablation and Group B- Non usage of compression bandages after the aforesaid surgical intervention). Out of 60, total 30 (50%) cases were in each group. Quality of life and therapeutic outcomes were noted, and patients were followed for 6 months. Quality of life outcomes compared based on SF-36 questionnaire showed more improvement in group A in all 8 domains. Other parameters like use of analgesics, itching, eczema, and increased leisure activities were better with use of compression bandages. Healing of ulcer was faster in Group A. Charing Cross varicose vein questionnaire also showed more improvement in group A (p value<0.001, <0.001, 0.003   at 1 month, 3 month and 6 month, respectively). In chronic venous ulcer, four-layer compressive bandaging after surgery enhances the healing rate of venous  Dengue is an endemic disease in tropical and subtropical regions of the world causing severe epidemic in India and is endemic in many parts of India, especially in metropolitan cities and towns. There are evidences which states that platelet parameters may have diagnostic and prognostic value in febrile thrombocytopenia including Platelet count, Mean platelet volume (MPV), Platelet distribution width (PDW), Plateletcrit (PCT). These parameters are obtained as a part of Complete Blood Count using Automated Hematology analyzers. Aim and Objectives: of this prospective study is 1) To evaluate the role platelet parameters in Dengue fever and also to determine the relationship of platelet parameters with platelet count and disease severity. 2) to assess the utility of platelet profile in patients with Dengue fever and understand its significance so that adverse outcomes of this rapidly spreading disease can be controlled to a greater extent. Material and Methods: This study was conducted on 133 confirmed cases of Dengue infected patients for a period of 9 months from April 2022 to December 2022. The Platelet parameters like Platelet count, MPV, PDW and Plateletcrit were measured by using BC 300 plus Mindray Automated Hematology Analyzer on venous samples collected in K3EDTA from 133 patients and was compared with disease severity (DF/DHF/DSS) . These 133 patients were grouped into three according to platelet count (100000). Results: Out of 133 patients, 17 patients who had platelet count ulcer with better quality of life outcomes.

Background: Chronic venous Insufficiency (CVI) is a commonest condition encountered in clinical practice that occurs due to venous valvular dysfunction in the superficial, deep, and/or perforating veins. The spectrum may vary from common varicose veins to more severe deep vein thrombosis and resulting local and systemic complications. Duplex ultrasonography plays vital role in understanding the spectrum of CVI.  Objectives: To evaluate the spectrum of colour duplex ultrasound findings in patients with chronic venous insufficiency clinical symptoms and signs.  Material & Methods: A prospective observational study was conducted in the department of Radio diagnosis of a tertiary care hospital. for a period two years. The study included 50 participants presenting with symptoms of pain, swelling, pedal oedema varicosities, erythema, and venous ulcer were included. In addition to detailed clinical assessment and review of past medical records,  Doppler ultrasonography of lower extremities was done. Results:  Age of the participants ranged from  11-70 years and 70% of participants were males. Among 50 participants 44 (88%) were positive on Doppler. In our study primary varicosities were seen in 29 cases ( 65.91%). Varicosities secondary to DVT were seen in 13 cases ( 29.55%), congenital causes were rare as noted in 2 cases (4.54%) of the total positive Doppler study cases. Swelling (36%) was the most common presenting symptom, followed by varicosity (20%). Prolonged hospitalization 5 (38.46%) is the major predisposing factor in patients with DVT. At least one perforator incompetence was seen in 42 (95.45%) cases. Below knee perforators seen in 30 (68.2%) cases, mid-calf perforators were involved in  26 (59.09%) cases and above ankle perforator incompetence was observed in 27(61.36%) cases. There was no statistically significant difference in the pattern of veins affected between male and female participants (P= 0.580). Conclusion: The colour duplex sonography is a safe, non-invasive, accurate, easily repeatable, economical, and widely available modality in the diagnosis of venous insufficiency and excludes underlying DVT, thus helping in providing valuable insights for the treatment of the patient.